Testing new pharmaceutical treatments is a complicated process. Very often, participants have preferences or hopes, either about what the test should measure or about what the outcome should be. Patients often enrol in the trial seeking access to experimental drugs while physicians usually have guesses about which treatment will work better. The sponsor will only recover millions of investment in the drug development if the trial is successful. Making sure that all these preferences do not shape the outcome of the test is crucial for its credibility. For that reason, treatments are often masked –“blinded” – so that neither physicians…
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